TLDR: Don’t restrict Calories. Restrict Insulin.
You need different levels or resolution to truly understand obesity.
At the highest level, it is the basic: calories in – calories out
But, there are things deeper than this. It’s more like f(calories in) – g(calories out) and this gets impacted due to that.
And also, f is connected with g!!! They are correlated somewhat.
Role of hormones
Fung says that obesity is a hormonal issue. But also genetic unfortunately.
Lets focus on the hormonal side. We need to go deep into how the cell stores and releases fat. What governs that. The calories in part is important because that energy is needed to do things like heat generation, muscle production, etc. But, some of it can be stored as fat.
It’s not the “excess” necessarily. That makes no sense to the body. The body is not keeping some precise track of this shit. Its all about the fucking hormones.
- You eat food
- Either your body heat increases
- Or it gets stored as fat
That branch is controlled by the fucking hormones. Out of whack hormones will shut the fucking body down. This is EXACTLY what is happening with me.
Ghrelin
The hunger hormone. Its a peptide hormone. When you loose weight naively you will increase this. You will feel hungrier and so you will nullify the work.
Protein, healthy fats, sleep fix this.
Leptin
The satiety hormone
It’s all about the insulin
Control this and its good
Incretin effect and Cephalic phase
Glucose is only correlated with Insulin. It’s not 1. Insulin is probably super high. Some things like Sucralose will increase insulin, but not glucose. Holy shit — whey protein spikes up insulin.
Look at Insulin Index
Glucagon-Like Peptide 1 (GLP-1) is a Incretin hormone
Hormonal theory of obesity
Insulin causes obesity. People who take insulin become fat. It influences your brain.
The goal is to LOWER INSULIN – it will lower SET POINT
Obesity is hormonal dysregulation of fat accumulation. Thats it.
Cortisol
This is another thing that causes the body to become fat.
High stress causes increase in glucose. But then that glucose is not burnt off, which causes elevation of Insulin.
Sleep deprivation causes high cortisol
The Rolex Life 
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